There are a few things that you should keep in mind when going for the best seafood Key West. You don't want to just go on the package and get what is recommended by the company. You need to take into account that there are plenty of different areas and places, so you will want to find out where the best seafood is, because it can vary significantly.
A popular place for seafood is Duval Street. You will find plenty of restaurants on this street with amazing food and people will be coming here all day, every day, because the quality of food here is superb. It's also really close to other attractions like art galleries and bars.